The integrated PPI network informed about the physical connection between proteins DSC2 and SSG2, while the pathway treemap illustrated the involvement of the genes DSC2 and DSG2 in cell apoptosis, and of MYH6 in muscle contraction, further confirming that they can contribute in different phenotypes that can be blended in an individual: arrhythmogenic cardiomyopathy and hypertrophic cardiomyopathy, respectively. The gene discussed is DSC2; the disease is hypertrophic cardiomyopathy.