CXCL8 and neoplasm: CXCL8-positive cases were positively correlated with gender (p = 0.0346), T grade (depth of tumour invasion: p < 0.0001), N grade (degree of lymph node metastasis: p < 0.0001), M grade (degree of distant metastasis: p = 0.0187) and tumour stage (p < 0.0001) (Table 1).