Patients with HER2/neu positive T1/2N0 tumors had a 10-year risk of tumor recurrence of 3% if they received trastuzumab (N = 73) compared to 11% if they did not receive trastuzumab (N = 159) in addition to other recommended local and systemic treatments (p = 0.074). The gene discussed is ERBB2; the disease is neoplasm.