CDK1 and malignant colon neoplasm: The miRNA miR-582-5p is known to suppress the proliferation of a variety of tumors, including hepatocellular carcinoma [41], colon cancer [42], and bladder cancer [43], and this suppression is thought to be related to the target genes CDK1, AKT3 [41], Rab27a [42], and FOXC1 [44].