Interestingly, our qPCR data demonstrate a significantly negative correlation between expression of Sdc-1 and IL-4 (r = - 0.564, P = 0.028), IL-17 (r = - 0.571, P = 0.026), and Foxp3 (r = - 0.607, P = 0.016) in breast carcinoma tissues of IBC patients (Fig 4). The gene discussed is IL4; the disease is breast carcinoma.