The patient underwent a video-assisted thoracoscopic surgery (VATS) right lower lobectomy with lymph nodes dissection and VATS wedge resection of right upper lobe, which confirmed moderately differentiated lung adenocarcinoma with epidermal growth factor receptor (EGFR) exon 19 deletions in the right lower lobe (pT2bN0) and minimally invasive, well-differentiated lung adenocarcinoma in the right upper lobe (pT1miN0). Here, EGFR is linked to lung adenocarcinoma.