GPT and obesity due to melanocortin 4 receptor deficiency: However, these pathological alterations could be attenuated by treatment with alisol A. In hepatic steatosis, excessive lipid deposits lead to hepatocellular injury42; moreover, a state of inflammation and accumulation of reactive oxygen species (ROS) could impair liver function.43 We found that alisol A markedly decreased serum levels of ALT and AST, suggesting that alisol A treatment had no hepatotoxic effects and was able to reverse obesity‐associated hepatocellular injury.