PHLPP2 and clear cell renal carcinoma: Fu et al found that up‐regulated miR‐32‐5p activated the PI3K/Akt pathway and led to drug resistance by promoting epithelial‐mesenchymal transition and angiogenesis.28 It has been reported that high expression of miR‐32‐5p was positively associated with poor survival outcome of hepatocellular carcinoma28 and gastric cancer.29 However, Wang et al reported that miR‐32‐5p significantly inhibited metastasis of clear cell renal cell carcinoma.30 PHLPP2 is a phosphatase‐regulating AKT(S473) phosphorylation and mTORC2.