In adults with T1D using CSII, faster aspart demonstrated an approximately three‐fold higher early insulin exposure and an approximately 100% greater glucose‐lowering effect within the first 30 minutes compared with IAsp.30 In addition, offset of exposure and offset of glucose‐lowering effect occurred 35 and 24 minutes earlier, respectively, with faster aspart than with IAsp. This evidence concerns the gene INS and type 1 diabetes mellitus.