IGF2 and Silver-Russell syndrome: Their deregulated expression is the cause of Beckwith–Wiedemann syndrome (H19, IGF2, KCNQ1OT1), Russel-Silver syndrome (H19, IGF2, KCNQ1OT1) and Uniparental disomy 14 (MEG3) and is also observed in several tumors (see Table 2).