Moreover, SEMA3F and its receptor Neuropilin-2/NRP2 were found to be highly expressed in human T-cell acute lymphoblastic leukemia/lymphoma primary cells, but SEMA3F was shown to inhibit the migration of malignant cells induced by CXCL12 and S1P (35). Here, NRP2 is linked to T-cell acute lymphoblastic leukemia.