PYCR1 and lung adenocarcinoma: Transwell assay demonstrated that the number of lung adenocarcinoma NCI-H1299 and A549 cells migrating to the inferior cavity in the PYCR1 silencing group was significantly reduced when compared with the vector control group (both P < 0.01; Figs. 4A–4C), indicating that PYCR1-silencing led to a significant reduction in the invasiveness of lung adenocarcinoma NCI-H1299 and A549 cells.