In recent years, in-depth analysis of malignant melanoma, prostate cancer, breast cancer, and other tumors further confirmed the importance of PYCR1 in the occurrence and development of tumors (Cai et al., 2018; Ding et al., 2017; Ye, Wu & Wang, 2018; Zeng et al., 2017). This evidence concerns the gene PYCR1 and Familial prostate cancer.