This is in keeping with less detailed data on circulating DC numbers in GBM patients.23,34 A cohort of cancer patients, including six with GBM, were found to have suppressed numbers of CD11c+ and CD123+ DC subsets.34 Since that study, CD11c+ DC have been further divided into the cDC2 (CD1c+) and cDC1 (CD141+) subsets analyzed in our study. This evidence concerns the gene THBD and cancer.