SIRT1 and ST Elevation Myocardial Infarction: The purpose of this study was to investigate the association between SIRT1 single nucleotide polymorphisms (rs7895833 A > G in the promoter region, rs7069102 C > G in intron 4, and rs2273773 C > T in exon 5) and development of premature ST-elevation myocardial infarction ≤45 years.