VEGFA and non-proliferative diabetic retinopathy: In an attempt to detect benefits in safety and efficacy as the primary comparative criteria, we performed a systematic review and meta-analysis of existing randomized controlled trials (RCTs) and high-quality comparative studies of cataract surgery with or without intravitreal anti-VEGF agent treatment for the treatment of DR including nonproliferative diabetic retinopathy (NPDR), proliferative diabetic retinopathy (PDR), or clinically significant macular edema (CSME).