PRKN and Parkinson disease: Since dUCH-knockdown Drosophila model was proved to have a close link to oxidative stress, other Drosophila models which related to mitochondrial damage and oxidative stress such as the PINK-1 and PARKIN mutation and the overexpressing of α-SYNUCLEIN are suggested to be the next potential models to provide more evidence about the activity and usability of purslane for Parkinson's disease [10, 39, 40].