Thus, difference in the expression levels of Mage-a2 detected in this work between mouse pluripotent and teratocarcinoma cells, likewise in MAGE-A2 expression between human ESCs and ECCs [34], may be characteristic for teratocarcinoma cells and contribute to their malignant phenotype with imbalance of proliferation and differentiation potentials. Here, MAGEA2 is linked to teratocarcinoma.