ERCC4 and Fanconi anemia: Indeed, it was demonstrated that XPF-ERCC1 participates in the Fanconi Anemia Pathway of DNA interstrand crosslinks repair (Bhagwat et al., 2009) and recently the XPF-ERCC1 complex has been shown to be involved in a sub-pathway of long-patch base excision repair (BER) involving 5′ gap formation (Woodrick et al., 2017).