PI3 and asthma: Though PHLDA1, IL-10, and PI3 did not present significant differences in protein levels between the severity subgroups (Figure 2), IL-10 showed higher levels in severe asthma patients (severe NA group: 200.60 ± 219.85 pg/ml and moderate-mild NA group: 105.27 ± 79.62 pg/ml; severe AA group: 211.49 ± 193.94 pg/ml and moderate-mild AA group 168.11 ± 136.13 pg/ml) (Figure 2E).