In a more recent study by Büll et al., using the same 3Fax-Peracetyl Neu5Ac inhibitor to treat C57BL/6JRccHsd WT mice transfected with a melanoma cell line, sialic acid blockade via intra-tumoral injection resulted in supressed melanoma tumor growth and enhanced tumor cell killing by CD8+ T-cells (57). The gene discussed is CD8A; the disease is neoplasm.