HDAC3 and Miyoshi myopathy: Consistent with this data, western blot analysis showed that HDAC3 is more highly expressed in the HS-5 bone marrow stromal cell line compared to MM.1S MM cell line (Fig. S1a), leading us to hypothesize that targeting HDAC3 in stroma could potentially have a profound impact on the MM survival and proliferation in the context of the BM microenvironment.