Flow-cytometric analysis showed no changes in surface-bound gp130 (also known as CD130) in MM cells and HS-5 cells after co-culture, regardless of HDAC3 expression, suggesting that CD130 shedding from MM cells may also contribute to increased sgp130 in HDAC3 KD plus MM cell co-cultures (Fig. S15b, 15c). The gene discussed is IL6ST; the disease is Miyoshi myopathy.