Of note, we also checked cBioPortal and found that these proteins related to angiogenesis (i.e. FASN, CLIC4, HSPB1, ARHGEF1, PHGDH, MYO1C, CAV1) are altered in a total of 242 melanoma patients out of a total of 471 (51.36%). This evidence concerns the gene CLIC4 and melanoma.