TNF and rheumatoid arthritis: Treatment of RA includes non-steroidal anti-inflammatory drugs (NSAIDs), disease modifying anti-rheumatic drugs (DMARDs), tumor necrosis factor alpha (TNF-α) inhibitors, IL-6 inhibitors, T-cell activation inhibitors, B-cell depletors, Kinase (JAK) inhibitors, immune-suppressants, and steroids.