To test this, we used AZD1152 (AZD), an AURKB/C inhibitor together with centrinone (or centrinone B), and found that only co-inhibition of AURKB/C and PLK4 prevented ACM-induced BCC migration (Fig. 3c) and suppressed protrusive activity (Fig. 3d). Here, PLK4 is linked to skin basal cell carcinoma.