When the efficacy of the two BFP to induce leukemia cell lysis was comparatively analyzed, NKG2D-CD16 again mediated more potent effects in short term cytotoxicity assays (Fig. 6d), while profoundly stronger effects were observed with NKG2D-CD3 in analyses of long term lysis (Fig. 6e). This evidence concerns the gene KLRK1 and leukemia.