Determination of NKG2DL surface levels using a NKG2D-Fc chimera to simultaneously detect all different NKG2DL confirmed positivity in all utilized samples with SFI levels between 2.4 and 37.6 (Fig. 5a) and the percentage of NKG2DL+ AML blasts within individual samples ranging between 26% and ~ 100% (Fig. 5b). The gene discussed is KLRK1; the disease is acute myeloid leukemia.