Tissue sections from intracranial CT2A-dmEGFRvIII-Luc (A) and SMA560-dmEGFRvIII-Luc (B) tumors were analyzed for the expression of PD-1 and FoxP3 on CD4+ and CD8+ T cells and PD-L1 on tumor cells. This evidence concerns the gene CD4 and neoplasm.