D2C7 is a novel monoclonal antibody (mAb) that reacts with both the wild-type epidermal growth factor receptor (EGFRwt) and the mutant EGFR variant III (EGFRvIII) (both of which are major glioblastoma driver oncogenes) overexpressed on the surface of cancer cells [6, 7]. This evidence concerns the gene EGFR and glioblastoma.