Following subgroup according to the presence of lymphopenia in the patients analysis showed that the mRNA and protein levels of RIG-I in T lymphocytes in patients with lymphopenia were significantly higher than those of patients without lymphopenia (0.121 ± 0.045 vs. 0.056 ± 0.032, p = 0.000; 0.379 ± 0.206 vs. 0.213 ± 0.084, p = 0.015) (Fig. 3b). The gene discussed is RIGI; the disease is lymphopenia.