Several therapeutic options were considered, including: cytotoxic chemotherapies commonly used in sarcoma such as doxorubicin and ifosfamide or gemcitabine and docetaxel; kinase inhibitors (such as imatinib or pazopanib); and programmed cell death-1 (PD-1) and PD-1 ligand (PD-L1) inhibitors. This evidence concerns the gene PDCD1 and sarcoma.