Moreover, to test the role of MSC in regulating de novo fatty acid synthesis, we analyzed the expression levels of key lipogenic enzymes in HCC cells, including ATP citrate lyase (ACLY), Acetyl-CoA carboxylase (ACC1), FASN, and Stearoyl-CoA desaturase 1 (SCD1). This evidence concerns the gene FASN and hepatocellular carcinoma.