Recent evidence indicates that miR-103 derived from hepatoma cells could be transmitted to endothelial cells via exosomes, which then inhibit the expression of VE-cadherin, p120-catenin (p120), and ZO-1 to attenuate the integrity of endothelial junctions, induce vascular leakiness, and consequently facilitate tumor metastasis [83]. The gene discussed is CTNND1; the disease is neoplasm.