Small gene panels—the Ion AmpliSeq RNA Fusion Lung Cancer Research Panel (Thermo Fisher Scientific) and Ion AmpliSeq Colon and Lung Cancer Panel (Thermo Fisher Scientific), with simultaneous sequencing of ALK, RET, ROS1, and NTRK1 fusion transcripts and hotspot and targeted regions of 22 genes implicated in colon and lung cancers, respectively—were applied prospectively [15]. This evidence concerns the gene ALK and lung carcinoma.