Alzheimer’s disease (AD) is a progressive, late-onset dementia and age-dependent neurodegenerative disorder characterized by an intracellular accumulation of tangles (insoluble hyperphosphorylated tau proteins) and extracellular plaques Aβ peptide deposition, i.e., (Aβ1–40 and Aβ1–42) [35]. This evidence concerns the gene MAPT and Alzheimer disease.