GLP1R and Hyperglycemia: This worsens ICU mortality but also leads to debilitating weakness in those surviving to ICU discharge.91 Hyperglucagonaemia is thought to be a key factor to provoke catabolism and hyperglycaemia in critical illness.92, 93 Given that a core attribute of GLP‐1 is to suppress glucagon release from pancreatic alpha‐cells,94 GLP‐1 has theoretical anticatabolic action as well as being effective in ameliorating stress hyperglycaemia.86, 95