Existing clinical guidelines for inpatient diabetes control only briefly discuss their role, if at all.4, 5, 6 Furthermore, the therapeutic benefit for GLP‐1 RA is being tested in a range of acute clinical settings including perioperative, coronary care, and critical care.7, 8, 9, 10, 11, 12, 13, 14, 15 This narrative review will outline the inpatient clinical areas in which GLP‐1 RA are being tested, the panoply of actions of GLP‐1 that offer the potential for benefit in acute illness, and the outcome measures reported so far. Here, GCG is linked to diabetes mellitus.