GLP1R and brain injury: It shares 53% sequence homology with GLP‐1 and has been used in a number of preclinical studies.33 Murine studies of ischaemic brain damage using Exendin‐434 and liraglutide35 show that they are capable of crossing the blood‐brain barrier to act directly on the brain to produce neuroprotective and anti‐inflammatory effects.36, 37 The neuroprotective properties that GLP‐1 RAs have shown in animal studies have also led to their evaluation in patients with brain injury after cardiac arrest.