A few SNPS had p-values suggestive of associations, including one obesity-related SNP, [rs2815752 (NEGR1), unadjusted p = 0.004] and several HTN-related SNPs [rs13139571 (GUCY1A3-GUCY1B3), rs11191548 (CYP17A1-NT5C2) and rs1801253 (ADRB1), each with unadjusted p = 0.01] (Table 2). This evidence concerns the gene ADRB1 and obesity due to melanocortin 4 receptor deficiency.