IL10 and asthma: In a study by Horohov, IFN‐γ mRNA was also increased in equine asthma exacerbation after antigenic challenge.30 Since IFN‐γ can contribute to an increase in the chronic pulmonary inflammation in asthmatic illnesses,69 and, in combination with IL‐10 and Tregs, can also have an inhibitory effect on the Th2 immune response,68 the results attained for IFN‐γ must be considered in relationship to the Tregs and the clinic.70