In the study by Terriou et al. (13), half of the CEBPA methylated T-ALL cases were CALM/AF10 positive (5/10), suggesting that the search of CALM/AF10 in CEBPA methylated AML could help distinguish between the immature T-ALL and myeloperoxidase negative AML. Here, MLLT10 is linked to acute lymphoblastic leukemia.