Interestingly, CD204 was significantly correlated with many immune checkpoints; of note, CD204 showed the strongest correlation with TIM‐3 and PD‐1 in both whole‐grade glioma (Figure 7A and 7) and GBM (Figure 7C and 7) and were further confirmed in our glioma samples (Figure S9). Here, PDCD1 is linked to central nervous system cancer.