PBX3 and colorectal carcinoma: For data analysis, we used not only univariate and traditional multivariate analysis but also a propensity score (PS) method, a newly proposed method that is used to reduce the likelihood of confounding bias when analyzing observational data from a cohort study in order to obtain results closer to a completely randomized control study.46 Therefore, in our 10‐year CRC cohort, we used PS‐based methods to comprehensively assess the effect of PBL PBX3 methylation on CRC prognosis.