These diseases have been described in several mammalian species, including dogs, cats, and Muntjak deer, and even in birds as Hexa deficiency has been observed in Flamingo's (Cork et al., 1977; Kanae et al., 2007; Kolicheski et al., 2017; Martin et al., 2004; Rahman et al., 2012; Torres et al., 2010; Zeng et al., 2008). Here, HEXA is linked to hyperinsulinemic hypoglycemia, familial, 4.