Earlier, Kispert et al demonstrated that Lp‐PLA2 inhibition by cigarette smoke extract induced cell motility in MDA‐MB‐231 cells and increased its adherence to the lung endothelium.201, 202 However, a recent study revealed possible beneficial effects of Lp‐PLA2 inhibition in advanced breast cancer, such as downregulation of epithelial‐mesenchymal transition (EMT) as well as cell migration and invasion. This evidence concerns the gene PLA2G7 and breast carcinoma.