Autophagy regulates the function of insulin‐sensitive tissues such as skeletal muscle, liver, visceral fat, and subcutaneous fat, as well as islet β cells (Yang et al., 2017), while deficient autophagy will lead to the impairment of islet β‐cell function and mass, thus eventually leading to the incidence of diabetes (Marrif & Al‐Sunousi, 2016). This evidence concerns the gene INS and diabetes mellitus.