MMP13 and chondrosarcoma: Matrix metalloproteinase-13 (MMP-13) also named collagenase-3 and MMP-3 named stromelysin-1 are of particular importance as they are responsible for the degradation of collagen and proteoglycans that are the major components of cartilage ECM, therefore they may play an important role in metastasis of chondrosarcoma cells.