Some genetic risk variants exhibit myeloma subtype-specific preference, e.g., a variant at CCND1 is associated with t(11;14)+ myeloma (Weinhold et al., 2013), whereas a variant at CBX7 is linked to subtypes of myeloma that do not carry the translocation (Chubb et al., 2013). The gene discussed is CBX7; the disease is plasma cell myeloma.