Chemerin is widely expressed throughout tissues and has myriad roles including the chemoattraction of innate cells [e.g., NK cells, macrophages, dendritic cells (DCs)] (9–11), functioning as an important antimicrobial agent in the skin (12), and is able to induce angiogenesis in human endothelial cells (13), suggesting chemerin may be a key factor in early immune responses to infection, injury, and/or inflammation. This evidence concerns the gene RARRES2 and infection.