CMKLR1 and neoplasm: Figure 3D shows comparable phenotypic expression of these markers between control and chemerin-expressing tumor lines. These data show that transduction with RARRES2 and expression/secretion of chemerin by EMT6 tumor cells does not appear to meaningfully impact in vitro growth or the immunophenotype of key surface proteins, and that secreted chemerin is functionally active and can induce migration of CMKLR1+ cells.