However, no significant differences in percentages of total T cells, CD4+ or CD8+ T cell subsets, B cells, NK cells, cDCs, pDCs, MDSCs, or macrophages among CD45+ TILs were detected between the two groups at an earlier time point in tumor growth (day 14, not shown), potentially suggesting that sufficient time is needed to establish an adequate concentration gradient of chemerin and resultant chemoattraction of effector cells. This evidence concerns the gene CD8A and neoplasm.