TNFAIP3 and autoimmune hepatitis: Further observation studies were needed to clarify the prognosis and the progression pattern of AIH patients with deleterious variants in TNFAIP3. In the present study, three deleterious variants in TNFAIP3 (c.116A > G, c.305A > G, and c.1897G > C) were detected in Japanese AIH patients, but none of them were reported to cause HA20.