TNFAIP3 and autoimmune hepatitis: No significant association with AIH was detected for the deleterious alleles in TNFAIP3. When AIH patients with cirrhosis at presentation were compared with the Japanese controls, a significant association was shown for the deleterious alleles in TNFAIP3 (P = 0.0180, odds ratio (OR) 4.28, 95% confidence interval (CI) 1.53–11.95, Table 1).