ERBB2 and cancer: Taking this into account, we conducted a phase II, multicenter, randomized, open-labeled clinical trial comparing eribulin plus gemcitabine (EG regimen) with PG regimen as first-line chemotherapy for patients with human epidermal growth factor receptor 2 (HER2)-negative MBC (the Korean Cancer Study Group [KCSG] BR13-11, Clinicaltrials.gov, NCT02263495) [11].