Other tumor type-specific covariates were histological subtype for BLCA (papillary vs. non-papillary), PAM50 subtype for BRCA [41] (Basal, Her2, LumA, or LumB, and the normal-like subtype was removed due to its small sample size), tumor grade for KIRC, IDH/CNA status for LGG (IDH wild-type, IDH mutant without chr1p and 19q co-deletion, IDH mutant with chr1p and 19q co-deletion), and Gleason score and PSA level for PRAD. The gene discussed is ERBB2; the disease is prostate adenocarcinoma.