Moreover, based on the TCGA data from http://gepia.cancer-pku.cn/, we also find that the OS rate of lung adenocarcinoma patients with higher TIM-1 mRNA expression level is significantly poorer compared with the patients with lower TIM-1 mRNA expression level (Fig. 4a, P = 0.0011), and the OS rate of lung squamous cell carcinoma patients with higher TIM-1 mRNA expression level also trends to be lower than that of the patients with lower TIM-1 mRNA expression level (Fig. 4b, P = 0.15). This evidence concerns the gene HAVCR1 and lung adenocarcinoma.