Figure 3c shows that, the OS rate of lung adenocarcinoma patients with higher TIM-1 expression level (H-score > 230) was significantly lower compared with the patients with lower TIM-1 expression level (H-score ≤ 230) (P = 0.0016, HR = 2.324, 95% CI 1.597–6.708). This evidence concerns the gene HAVCR1 and lung adenocarcinoma.