BRCA1 associated RING domain 1 (BARD1), CBX3, cathepsin S (CTSS), interferon-related developmental regulator 1 (IFRD1), signal transducer and activator of transcription 1 (STAT1), and myelin-associated oligodendrocytic basic protein (MOBP) were significantly and specifically differentially expressed in GBM. The gene discussed is CTSS; the disease is glioblastoma.