However, in contrast to the trend towards increased IL-10 expression with clenbuterol treatment at 4 h post-stroke, IL-10 mRNA expression was actually reduced by 4.78-fold in peri-infarct cortex of clenbuterol-treated mice relative to saline-treated mice at the 3-day sub-acute time point (Fig. 9b). This evidence concerns the gene IL10 and Stroke.