To determine if Adrb2 knockout had more specific effects on microglia/MDM morphology and proliferation after stroke, we also immunostained for Iba1 and BrdU and quantified numbers of Iba1-positive and Iba1/ BrdU-double-positive cells in the peri-infarct cortex of Adrb2cKO and Adrb2WT mice. Here, AIF1 is linked to stroke disorder.