We counted Iba1-positive cells in confocal z-stacks taken in the peri-infarct cortex, which revealed a 1.7-fold reduction in Iba1+ cell density in the peri-infarct cortex of clenbuterol-treated mice compared to saline-treated mice 3 days after photothrombotic stroke (Fig. 2a, b). Here, AIF1 is linked to stroke disorder.